Дексалгин Раствор, ампулы, 5 шт, 2 мл, 25 мг, для внутривенного введения

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Состав); - язвенная болезнь желудка и двенадцатиперстной кишки; - желудочно-кишечные кровотечения в анамнезе, другие активные кровотечения (в т.ч. подозрение на внутричерепное кровотечение), антикоагулянтная терапия; - желудочно-кишечные заболевания (болезнь Крона, неспецифический язвенный колит); - тяжелые нарушения функции печени (10-15 баллов по шкале Чайлд-Пью); - тяжелые нарушения функции почек (клиренс креатинина \u003c 50 мл/мин); - бронхиальная астма (в т.ч. в анамнезе); - тяжелая сердечная недостаточность; - лечение болевого синдрома при аортокоронарном шунтировании; - геморрагический диатез или другие нарушения коагуляции; - детский возраст."]}},{"type":"paragraph","data":{"text":"Дексалгин противопоказан для невраксиального (эпидурального или подоболочечного, внутриоболочечного) введения из-за входящего в состав препарата этанола."}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Применение препарата Дексалгин при беременности и в период лактации противопоказано."}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Дексалгин предназначен для в/в и в/м введения.; Рекомендуемая доза для взрослых: 50 мг каждые 8-12 ч. При необходимости возможно повторное введение препарата с 6-часовым интервалом. Суточная доза составляет 150 мг.; У пациентов пожилого возраста и пациентов с нарушением функции печени и/или почек терапию препаратом Дексалгин следует начинать с более низких доз; суточная доза составляет 50 мг.; Дексалгин предназначен для краткосрочного (не более 2 дней) применения в период острого болевого синдрома. В дальнейшем возможен перевод пациента на анальгетики для приема внутрь.; Правила приготовления и введения растворов; Содержимое одной ампулы (2 мл) медленно вводят глубоко в/м.; Содержимое одной ампулы (2 мл) вводят путем медленной в/в инъекции продолжительностью не менее 15 сек.; Содержимое одной ампулы (2 мл) разводят в 30-100 мл физиологического раствора, раствора глюкозы или раствора Рингера (лактата). Раствор следует готовить в асептических условиях и всегда защищать от воздействия дневного света. Разбавленный раствор (должен быть прозрачным) вводят путем медленной в/в инфузии продолжительностью 10-30 мин.;"}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Возможные побочные эффекты при применении декскетопрофена трометамола, как и при применении других препаратов декскетопрофена, приведены ниже по нисходящей частоте возникновения: часто (1-10 % пациентов), нечасто (0,1-1 % пациентов) редко (0,01-0,1 % пациентов), очень редко (менее 0,01 % пациентов), включая отдельные сообщения.; Со стороны кровеносной и лимфатической систем; Редко: анемия.; Очень редко: нейтропения, тромбоцитопения.; Со стороны центральной нервной системы; Нечасто: головная боль, головокружение, бессонница, сонливость.; Редко: парестезия.; Со стороны органов чувств; Нечасто: нечеткость зрения.; Редко: шум в ушах.; Со стороны сердечно-сосудистой системы; Нечасто: артериальная гипотензия, чувство жара, гиперемия кожных покровов.; Редко: экстрасистолия, тахикардия, артериальная гипертензия, периферический отек, поверхностный тромбофлебит.; Со стороны дыхательной системы; Редко: брадипноэ.; Очень редко: бронхоспазм, диспноэ.; Со стороны желудочно-кишечного тракта; Часто: тошнота, рвота.; Нечасто: абдоминальная боль, диспепсия, диарея, запор, гематемезис, сухость во рту.; Редко: эрозивно-язвенные поражения органов ЖКТ, включая кровотечения и перфорации, анорексия.; Очень редко: поражение поджелудочной железы.; Со стороны печени и желчного пузыря; Редко: повышение активности печеночных ферментов, желтуха.; Очень редко: поражение печени.; Со стороны мочевыделительной системы; Редко: полиурия, почечная колика.; Очень редко: нефрит или нефротический синдром.; Со стороны репродуктивной системы; Редко: у женщин – нарушение менструального цикла, у мужчин – нарушение функции предстательной железы.; Со стороны опорно-двигательного аппарата; Редко: мышечный спазм, затруднение движений в суставах.; Со стороны кожных покровов; Нечасто: дерматит, сыпь, потливость.; Редко: крапивница, угревая сыпь.; Очень редко: тяжелые кожные реакции (синдром Стивенса-Джонсона, синдром Лайелла), ангионевротический отек, аллергический дерматит, фотосенсибилизация.; Со стороны обмена веществ; Редко: гипергликемия, гипогликемия, гипертриглицеридемия.; Со стороны лабораторных показателей; Редко: кетонурия, протеинурия.; Местная и общая реакции; Часто: боль в месте инъекции.; Нечасто: воспалительная реакция, гематома, геморрагии в месте инъекции; чувство жара, озноб, утомление.; Редко: боль в спине, обморок, лихорадка.; Очень редко: анафилактический шок, отек лица.; Прочие нарушения: асептический менингит, возникающий преимущественно у пациентов с системной красной волчанкой или смешанными заболеваниями соединительной ткани, гематологические нарушения (пурпура, апластическая и гемолитическая анемии, редко – агранулоцитоз и гипоплазия костного мозга).;"}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Симптомы: тошнота, анорексия, абдоминальная боль, головная боль, головокружение, дезориентация, бессонница.; Лечение: симптоматическая терапия; при необходимости – промывание желудка, диализ.;"}}]},{"id":9,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"У пациентов с нарушениями со стороны желудочно-кишечного тракта или желудочно-кишечными заболеваниями в анамнезе необходим постоянный контроль. В случае возникновения желудочно-кишечного кровотечения или язвы терапию препаратом Дексалгин следует отменить.; Так как все НПВП могут ингибировать агрегацию тромбоцитов и увеличивать время кровотечения вследствие замедления синтеза простагландинов, в контролируемых клинических исследованиях было изучено одновременное назначение декскетопрофена трометамола и препаратов низкомолекулярного гепарина в профилактических дозах в послеоперационном периоде. Никакого воздействия на параметры коагуляции не наблюдалось. Тем не менее, при одновременном назначении препарата Дексалгин с другими препаратами, влияющими на свертываемость крови, необходим тщательный медицинский контроль.; Как и другие НПВП, Дексалгин может приводить к повышению уровня креатинина и азота в плазме крови. Как и другие ингибиторы синтеза простагландинов, Дексалгин может оказывать побочное действие на мочевыделительную систему, что может привести к развитию гломерулонефрита, интерстициального нефрита, папиллярного некроза, нефротического синдрома и острой почечной недостаточности.; Как и в случае других НПВП, на фоне терапии препаратом Дексалгин может наблюдаться небольшое преходящее повышение некоторых печеночных показателей, а также значительное повышение уровня аспарагиновой и аланиновой трансаминаз (АсТ и АлТ) в сыворотке крови. При этом контроль печеночной и почечной функций необходим у лиц пожилого возраста. В случае значительного повышения соответствующих показателей Дексалгин следует отменить.; Как и другие НПВП, декскетопрофена трометамол может маскировать симптомы инфекционных заболеваний. В случае обнаружения признаков бактериальной инфекции или ухудшения самочувствия на фоне терапии препаратом Дексалгин пациенту необходимо сразу обратиться к врачу.; В каждой ампуле препарата Дексалгин содержится 200 мг этанола.; Влияние на способность к вождению автотранспорта и управлению механизмами; В связи с возможным головокружением и сонливостью в период приема препарата Дексалгин способность к концентрации внимания и быстрота психомоторных реакций у пациентов могут снижаться.;"}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"Нестероидный противовоспалительный препарат (НПВП). Оказывает анальгезирующее, противовоспалительное и жаропонижающие действие. Механизм действия связан с ингибированием синтеза простагландинов на уровне ЦОГ-1 и ЦОГ-2.; Анальгезирующее действие наступает через 30 мин после парентерального введения. 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