- стимулирует продукцию антител к различным антигенам
инфекционной природы;
- увеличивает содержание CD4+ Т клеток и NK
клеток;
- повышает функциональную активность нейтрофилов и CD8+Т
клеток, являющихся ключевыми звеньями защиты организма от бактерий, вирусов и
грибов;
- подавляет репликацию вирусов.
Благодаря указанным фармакологическим свойствам, Гепон
повышает резистентность организма в отношении инфекций, вызванных вирусами,
бактериями и грибами. Гепон оказывает противовоспалительный эффект в течение
1-2 дней после применения.
Фармакокинетика препарата
не изучалась в связи с его пептидной природой.
Показания к применению
В составе
комбинированной терапии: лечение инфекций слизистых оболочек и кожи, вызванных грибами Candida; снижения
интенсивности воспаления (покраснение, отек, зуд, жжение, боль) слизистых оболочек и кожи, сухости слизистых
оболочек. Профилактика кандидоза слизистых оболочек и кожи на фоне терапии
антибиотиками.
Противопоказания
Индивидуальная гиперчувствительность к Гепону. Детский возраст до 12 лет.
Применение при беременности и в период грудного вскармливания
Применение возможно только, если
потенциальная польза для матери превышает возможный вред для плода. Гепон не
рекомендуется для применения в период грудного вскармливания. При необходимости
применения препарата грудное вскармливание следует прекратить.
Способ применения и дозы
Применяют местно, наружно.
Перед применением препарат растворяют в воде
для инъекций (при наружном применении препарата, т.е. для обработки кожи) или в
0,9 % растворе натрия хлорида (при местном применении препарата, т.е. для
обработки слизистых оболочек).
Способ приготовления препарата перед
применением:
1. Удалить защитную часть алюминиевого колпачка с
резиновой пробки флакона с лекарственным препаратом. Если лекарственный
препарат в ампуле, вскрыть ампулу.
2. Вскрыть ампулу с растворителем (вода для инъекций). В
качестве растворителя также может использоваться 0,9 % раствор натрия хлорида.
3. Надеть иглу на одноразовый шприц
4. Набрать в шприц растворитель
5. Проколоть иглой со шприцем резиновую пробку флакона с
лекарственным препаратом и влить во флакон 2 – 2,5 мл растворителя. Если
лекарственный препарат в ампуле, влить во вскрытую ампулу также 2 – 2,5 мл
растворителя.
6. Не извлекая иглу, легкими колебательными движениями в
течение примерно 1 минуты, полностью растворить содержимое флакона (ампулы).
7. Набрать полученный раствор в шприц с остатком
растворителя.
8. Извлечь шприц с иглой из флакона (ампулы), легкими
колебательными движениями в течение примерно 1 минуты, полностью перемешать
раствор в шприце.
9. Снять иглу со шприца.
10. Использовать шприц
в качестве дозирующего устройства для инстилляций, нанесения на кожу и
слизистые оболочки или смачивания марлевых салфеток.
Рекомендуемая доза для взрослых и детей 12 лет и старше составляет 1-2
мг в виде 0,02 % раствора для местной обработки слизистых оболочек один раз в
день.
Рекомендуемая доза для взрослых и детей 12 лет и старше составляет 1-2
мг в виде 0,04 % раствора для обработки
кожи один раз в день.
Для лечения инфекций слизистых оболочек, вызванных грибами Candida, рекомендуется местное применение Гепона путем нанесения на пораженные
участки слизистых оболочек (вульвы, влагалища, уретры) 0,02 % раствором, курсом в
3 применения (один раз в сутки) с интервалом 1-3 дня между нанесениями.
Для лечения инфекций кожи, вызванных грибами Candida, рекомендуется наружное
применение Гепона путем нанесения на пораженные участки кожи 0,04 % раствором, курсом в 3 применения
(один раз в сутки) с интервалом 1-3 дня между нанесениями.
При вульвовагините, уретрите у женщин применяют обработку 0,02 % раствором
Гепона слизистой вульвы, влагалища, а также примочки на пораженные участки
кожи, прилегающие ко входу во влагалище 0,04 % раствором Гепона.
При уретрите и баланопостите у мужчин применяют инстилляции 0,02 % раствором Гепона в
уретру и примочки на пораженные участки кожи 0,04 % раствором Гепона.
Обработку слизистых оболочек и кожи проводят курсом в 3 приема (один
раз в сутки) с интервалом 1-3 дня.
Профилактика
кандидоза слизистых оболочек на фоне терапии антибиотиками. Рекомендуется проводить примочки 0,02 % раствором
Гепона во время курса лечения антибиотиком. Обработку слизистых оболочек проводят курсом
в 3 приема (один раз в сутки) с интервалом 1-3 дня.
Профилактика
кандидоза кожи на фоне терапии антибиотиками: рекомендуется
проводить
примочки 0,04 % раствором Гепона во время курса лечения антибиотиком. Обработку кожи
проводят курсом в 3 приема (один раз в сутки) с интервалом 1-3 дня.
Для снижения интенсивности воспаления и сухости слизистые оболочки
следует обрабатывать 0,02 % раствором Гепона. Обработку слизистых оболочек
проводят курсом в 3 приема (один раз в сутки) с интервалом 1-3 дня.
Для снижения интенсивности воспаления кожи: накладывать марлевые
салфетки, смоченные 0,04 % раствором Гепона. Обработку кожи проводят курсом в 3
приема (один раз в сутки) с интервалом 1-3 дня.
Побочное действие
Не обнаружено. Возможны аллергические реакции. Если любые из указанных в
инструкции побочных эффектов усугубляются, или Вы заметили любые другие
побочные эффекты, не указанные в инструкции, сообщите об этом врачу.
Передозировка
Симптомы передозировки не описаны.
Взаимодействие с другими лекарственными средствами
Не описано.
Влияние на способность управлять автомобилем и движущимися механизмами
Препарат не влияет на способность управлять транспортными средствами,
движущимися механизмами и заниматься другими потенциально опасными видами
деятельности, требующими повышенной концентрации внимания и быстроты
психомоторных реакций.
Форма выпуска
Лиофилизат для
приготовления раствора для местного и наружного применения, 1 мг, 2 мг.
По 1 мг или 2 мг препарата во флаконы стеклянные или в ампулы
из нейтрального стекла.
1, 2, 3 флакона или ампулы с инструкцией по медицинскому
применению помещают в пачку картонную.
По 1 флакону или ампуле с препаратом, 1
ампуле с водой для инъекций 5 мл вместе с инструкцией по медицинскому применению
помещают в пачку картонную (комплект).
По 1 флакону или ампуле с препаратом, 1
ампуле с водой для инъекций 5 мл, 1 шприцу одноразовому стерильному вместе с
инструкцией по медицинскому применению помещают в пачку картонную (комплект).
По 30 флаконов или ампул вместе с 10 инструкциями
по медицинскому применению помещают в пачку картонную (Для стационаров).
На пачку возможно нанесение этикеток
контроля первого вскрытия.
Условия хранения
Хранить в защищенном от света месте при
температуре не выше 25° С.
Хранить в местах, недоступных для детей.
Срок годности
4 года. Не использовать по истечении срока годности.
Условия отпуска
Отпускают без рецепта.
Производитель
ООО «ИММАФАРМА», 123098, Москва, ул. Гамалеи, д. 18, стр. 11.
Организация, принимающая претензии потребителей
ОАО «Авексима»
125284, Россия, г. Москва,
Ленинградский проспект, д. 31А, стр. 1.
Тел.:+7(495)258-45-28.
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
Начните сравнивать цены и заказывать лекарства прямо в приложении
Наведите камеру на QR-код, чтобы скачать
Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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номер","slug":"","body":[{"type":"paragraph","data":{"text":" P N000015/01"}}]},{"id":11,"name":"Лекарственная форма","slug":"","body":[{"type":"paragraph","data":{"text":"лиофилизат для приготовления раствора для местного и наружного\nприменения."}}]},{"id":1,"name":"Состав","slug":"ingredients","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"\u003ci\u003eДействующее\nвещество\u003c/i\u003e: "}},{"type":"paragraph","data":{"text":"треонил-глутамил-лизил-лизил-аргинил-аргинил-глутамил-треонил-валил-глутамил-аргинил-глутамил-лизил-глутамат\n(Гепон) 1мг, 2 мг\u003cb\u003e\u003c/b\u003e"}}]},{"id":12,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"Лиофилизированный порошок белого цвета, без запаха."}}]},{"id":13,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"иммуномодулирующее средство"}}]},{"id":2,"name":"Фармакологические свойства","slug":"pharmacologic_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003eФармакодинамика\u003c/i\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Гепон оказывает\nиммуномодулирующее и противовирусное действие: "}},{"type":"paragraph","data":{"text":"- вызывает продукцию альфа- и бета- интерферонов;"}},{"type":"paragraph","data":{"text":"- мобилизует и активирует макрофаги;"}},{"type":"paragraph","data":{"text":"- ограничивает выработку провоспалительных цитокинов\n(интерлейкины - 1, 6, 8 и фактор некроза опухоли);"}},{"type":"paragraph","data":{"text":"- стимулирует продукцию антител к различным антигенам\nинфекционной природы; "}},{"type":"paragraph","data":{"text":"- увеличивает содержание CD4\u003csup\u003e+ \u003c/sup\u003eТ клеток и NK\nклеток;"}},{"type":"paragraph","data":{"text":"- повышает функциональную активность нейтрофилов и CD8\u003csup\u003e+\u003c/sup\u003eТ\nклеток, являющихся ключевыми звеньями защиты организма от бактерий, вирусов и\nгрибов;"}},{"type":"paragraph","data":{"text":"- подавляет репликацию вирусов."}},{"type":"paragraph","data":{"text":"Благодаря указанным фармакологическим свойствам, Гепон\nповышает резистентность организма в отношении инфекций, вызванных вирусами,\nбактериями и грибами. Гепон оказывает противовоспалительный эффект в течение\n1-2 дней после применения."}},{"type":"paragraph","data":{"text":"\u003cb\u003eФармакокинетика \u003c/b\u003eпрепарата\nне изучалась в связи с его пептидной природой."}}]},{"id":3,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"В составе\nкомбинированной терапии: лечение инфекций слизистых оболочек и кожи, вызванных грибами \u003ci\u003eCandida\u003c/i\u003e\u003ci\u003e;\u003c/i\u003e снижения\nинтенсивности воспаления (покраснение, отек, зуд, жжение, боль) слизистых оболочек и кожи, сухости слизистых\nоболочек. Профилактика кандидоза слизистых оболочек и кожи на фоне терапии\nантибиотиками.\u003ci\u003e\u003c/i\u003e"}}]},{"id":4,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Индивидуальная гиперчувствительность к Гепону. Детский возраст до 12 лет."}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Применение возможно только, если\nпотенциальная польза для матери превышает возможный вред для плода. Гепон не\nрекомендуется для применения в период грудного вскармливания. При необходимости\nприменения препарата грудное вскармливание следует прекратить. "}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Применяют местно, наружно."}},{"type":"paragraph","data":{"text":"Перед применением препарат растворяют в воде\nдля инъекций (при наружном применении препарата, т.е. для обработки кожи) или в\n0,9 % растворе натрия хлорида (при местном применении препарата, т.е. для\nобработки слизистых оболочек). "}},{"type":"paragraph","data":{"text":"Способ приготовления препарата перед\nприменением:"}},{"type":"paragraph","data":{"text":"1. Удалить защитную часть алюминиевого колпачка с\nрезиновой пробки флакона с лекарственным препаратом. Если лекарственный\nпрепарат в ампуле, вскрыть ампулу."}},{"type":"paragraph","data":{"text":"2. Вскрыть ампулу с растворителем (вода для инъекций). В\nкачестве растворителя также может использоваться 0,9 % раствор натрия хлорида."}},{"type":"paragraph","data":{"text":"3. Надеть иглу на одноразовый шприц"}},{"type":"paragraph","data":{"text":"4. Набрать в шприц растворитель"}},{"type":"paragraph","data":{"text":"5. Проколоть иглой со шприцем резиновую пробку флакона с\nлекарственным препаратом и влить во флакон 2 – 2,5 мл растворителя. Если\nлекарственный препарат в ампуле, влить во вскрытую ампулу также 2 – 2,5 мл\nрастворителя."}},{"type":"paragraph","data":{"text":"6. Не извлекая иглу, легкими колебательными движениями в\nтечение примерно 1 минуты, полностью растворить содержимое флакона (ампулы)."}},{"type":"paragraph","data":{"text":"7. Набрать полученный раствор в шприц с остатком\nрастворителя. "}},{"type":"paragraph","data":{"text":"8. Извлечь шприц с иглой из флакона (ампулы), легкими\nколебательными движениями в течение примерно 1 минуты, полностью перемешать\nраствор в шприце. "}},{"type":"paragraph","data":{"text":"9. Снять иглу со шприца."}},{"type":"paragraph","data":{"text":"10. Использовать шприц\nв качестве дозирующего устройства для инстилляций, нанесения на кожу и\nслизистые оболочки или смачивания марлевых салфеток."}},{"type":"paragraph","data":{"text":"Рекомендуемая доза для взрослых и детей 12 лет и старше составляет 1-2\nмг в виде 0,02 % раствора для местной обработки слизистых оболочек один раз в\nдень."}},{"type":"paragraph","data":{"text":"Рекомендуемая доза для взрослых и детей 12 лет и старше составляет 1-2\nмг в виде 0,04 % раствора для обработки\nкожи один раз в день."}},{"type":"paragraph","data":{"text":"Для лечения инфекций слизистых оболочек, вызванных грибами \u003ci\u003eCandida\u003c/i\u003e\u003ci\u003e, \u003c/i\u003eрекомендуется местное применение Гепона путем нанесения на пораженные\nучастки слизистых оболочек (вульвы, влагалища, уретры) 0,02 % раствором, курсом в\n3 применения (один раз в сутки) с интервалом 1-3 дня между нанесениями."}},{"type":"paragraph","data":{"text":"Для лечения инфекций кожи, вызванных грибами \u003ci\u003eCandida\u003c/i\u003e\u003ci\u003e, \u003c/i\u003eрекомендуется наружное\nприменение Гепона путем нанесения на пораженные участки кожи 0,04 % раствором, курсом в 3 применения\n(один раз в сутки) с интервалом 1-3 дня между нанесениями."}},{"type":"paragraph","data":{"text":"При вульвовагините, уретрите у женщин применяют обработку 0,02 % раствором\nГепона слизистой вульвы, влагалища, а также примочки на пораженные участки\nкожи, прилегающие ко входу во влагалище 0,04 % раствором Гепона."}},{"type":"paragraph","data":{"text":"При уретрите и баланопостите у мужчин применяют инстилляции 0,02 % раствором Гепона в\nуретру и примочки на пораженные участки кожи 0,04 % раствором Гепона. "}},{"type":"paragraph","data":{"text":"Обработку слизистых оболочек и кожи проводят курсом в 3 приема (один\nраз в сутки) с интервалом 1-3 дня."}},{"type":"paragraph","data":{"text":"Профилактика\nкандидоза слизистых оболочек на фоне терапии антибиотиками. Рекомендуется проводить примочки 0,02 \u003ci\u003e% \u003c/i\u003eраствором\nГепона во время курса лечения антибиотиком. Обработку слизистых оболочек проводят курсом\nв 3 приема (один раз в сутки) с интервалом 1-3 дня."}},{"type":"paragraph","data":{"text":"Профилактика\nкандидоза кожи на фоне терапии антибиотиками: рекомендуется\nпроводить\nпримочки 0,04 \u003ci\u003e% \u003c/i\u003eраствором Гепона во время курса лечения антибиотиком. Обработку кожи\nпроводят курсом в 3 приема (один раз в сутки) с интервалом 1-3 дня."}},{"type":"paragraph","data":{"text":"Для снижения интенсивности воспаления и сухости слизистые оболочки\nследует обрабатывать 0,02 % раствором Гепона. Обработку слизистых оболочек\nпроводят курсом в 3 приема (один раз в сутки) с интервалом 1-3 дня."}},{"type":"paragraph","data":{"text":"Для снижения интенсивности воспаления кожи: накладывать марлевые\nсалфетки, смоченные 0,04 % раствором Гепона. Обработку кожи проводят курсом в 3\nприема (один раз в сутки) с интервалом 1-3 дня."}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Не обнаружено. Возможны аллергические реакции. Если любые из указанных в\nинструкции побочных эффектов усугубляются, или Вы заметили любые другие\nпобочные эффекты, не указанные в инструкции, сообщите об этом врачу."}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Симптомы передозировки не описаны."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Не описано."}}]},{"id":16,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Препарат не влияет на способность управлять транспортными средствами,\nдвижущимися механизмами и заниматься другими потенциально опасными видами\nдеятельности, требующими повышенной концентрации внимания и быстроты\nпсихомоторных реакций."}}]},{"id":17,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Лиофилизат для\nприготовления раствора для местного и наружного применения, 1 мг, 2 мг."}},{"type":"paragraph","data":{"text":"По 1 мг или 2 мг препарата во флаконы стеклянные или в ампулы\nиз нейтрального стекла."}},{"type":"paragraph","data":{"text":"1, 2, 3 флакона или ампулы с инструкцией по медицинскому\nприменению помещают в пачку картонную."}},{"type":"paragraph","data":{"text":"По 1 флакону или ампуле с препаратом, 1\nампуле с водой для инъекций 5 мл вместе с инструкцией по медицинскому применению\nпомещают в пачку картонную (комплект). "}},{"type":"paragraph","data":{"text":"По 1 флакону или ампуле с препаратом, 1\nампуле с водой для инъекций 5 мл, 1 шприцу одноразовому стерильному вместе с\nинструкцией по медицинскому применению помещают в пачку картонную (комплект)."}},{"type":"paragraph","data":{"text":"По 30 флаконов или ампул вместе с 10 инструкциями\nпо медицинскому применению помещают в пачку картонную (Для стационаров)."}},{"type":"paragraph","data":{"text":"На пачку возможно нанесение этикеток\nконтроля первого вскрытия."}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить в защищенном от света месте при\nтемпературе не выше 25° С. "}},{"type":"paragraph","data":{"text":"Хранить в местах, недоступных для детей."}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"4 года. Не использовать по истечении срока годности\u003cb\u003e.\u003c/b\u003e"}}]},{"id":20,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают без рецепта."}}]},{"id":21,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"ООО «ИММАФАРМА», 123098, Москва, ул. Гамалеи, д. 18, стр. 11."}}]},{"id":22,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"ОАО «Авексима»"}},{"type":"paragraph","data":{"text":"125284, Россия, г. Москва,\nЛенинградский проспект, д. 31А, стр. 1. 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