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Постмаркетинговый опыт применения Синвиск/Synvisc показал, что в некоторых случаях экссудация может быть значительной и вызывать более продолжительный болевой синдром. В этих случаях необходимо произвести пункцию сустава и удаление экссудата с его последующим анализом для исключения инфекции и микрокристаллической артропатии. Обычно такие реакции бесследно проходят в течение нескольких дней. Наличие таких реакций не влияет на эффективность лечения. В ходе клинических исследований Синвиск/Synvisc редко отмечались внутрисуставные инфекции. Постмаркетинговый опыт применения Выявил наличие следующих системных реакций, которые иногда появляются при введении Синвиск/Synvisc - сыпь, крапивница, зуд, тошнота, головная боль, Головокружение озноб, мышечные судороги, Парестезии периферические отеки (в том числе, и на лице), слабость, затруднение дыхания, покраснение кожи."}}]},{"id":9,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"1. Перед каждой инъекцией Синвиск/Synvisc следует удалить синовиальную жидкость или внутрисуставной экссудат. 2. Нельзя использовать Синвиск/Synvisc в случае, если упаковка вскрыта или повреждена. 3. Синвиск/Synvisc следует вводить при комнатной температуре. 4. Для удаления шприца из блистера (или футляра), его следует взять за корпус, не касаясь штока поршня. 5. Синвиск/Synvisc следует вводить в строгом соответствии с правилами асептики, поэтому необходимо соблюдать соответствующие меры предосторожности при удалении со шприца защитного колпачка. 6. Необходимо повернуть колпачок перед тем, как его снять для минимизации утечек препарата. 7. Следует использовать соответствующий размер (18-22) и длину иглы, в зависимости от сустава, в который предполагается инъекция. 8. Для предотвращения утечки препарата во время введения удерживайте иглу в плотном контакте со шприцем. 9. Не закручивайте и не прикладывайте чрезмерного усилия при фиксации иглы или снятии колпачка, так как это может привести к поломке кончика шприца. 10. Не подвергайте Синвиск/Synvisc повторной стерилизации. 11. Вводите Синвиск/Synvisc строго в суставное пространство. При необходимости используйте рентгеноскопическое определение направления инъекции, особенно при инъекции в тазобедренный и плечевой сустав. 12. Содержимое шприца предназначено только для однократного использования. 13. При использовании рентгеноскопии для определения направления инъекции, можно использовать ионное или неионное контрастное вещество. На каждые 2 мл Синвиск/Synvisc должно быть использовано не более 1 мл контрастного вещества."}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"Синвиск/Synvisc является стерильной, апирогенной, вязкоэластичной жидкостью, содержащей гиланы. 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