Аэрозоль для ингаляций дозированный в виде бесцветного или слабо-желтого прозрачного раствора. 1 доза формотерола фумарат 12 мкг Вспомогательные вещества: этанол, хлороводородная кислота, норфлуран (1,1,1,2-тетрафторэтан).
Фармакологические свойства
Бета-адреномиметик. Действует преимущественно на β .2-адренорецепторы. Оказывает бронхолитическое действие, купирует и предупреждает бронхоспазм. Ингибирует высвобождение гистамина, лейкотриенов и простагландина D2 из тучных клеток, базофилов и сенсибилизированных клеток бронхоальвеолярного дерева.
Показания к применению
Профилактика и лечение бронхоспазма у больных с обструктивным бронхитом, бронхиальной астмой.
Применение при беременности и в период грудного вскармливания
Передозировка
Побочное действие
Не следует комбинировать формотерол с адреномиметическими средствами, ингибиторами МАО, трициклическими антидепрессантами (повышается риск развития побочных эффектов со стороны сердечно-сосудистой системы). При одновременном применении производные ксантина, ГКС, диуретики усиливают вероятность гипокалиемического действия препарата. При одновременном применении хинидин, дизопирамид, прокаинамид, фенотиазины, антигистаминные препараты, трициклические антидепрессанты повышают риск развития желудочковых аритмий. Бета-адреноблокаторы (в т.ч. в форме глазных капель) частично или полностью блокируют действие формотерола.
Особые указания
Не следует комбинировать формотерол с адреномиметическими средствами, ингибиторами МАО, трициклическими антидепрессантами (повышается риск развития побочных эффектов со стороны сердечно-сосудистой системы). При одновременном применении производные ксантина, ГКС, диуретики усиливают вероятность гипокалиемического действия препарата. При одновременном применении хинидин, дизопирамид, прокаинамид, фенотиазины, антигистаминные препараты, трициклические антидепрессанты повышают риск развития желудочковых аритмий. Бета-адреноблокаторы (в т.ч. в форме глазных капель) частично или полностью блокируют действие формотерола.
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