Ксимелин Экстра Спрей, флакон, 10 мл, 84+70 мкг/доза, назальный, для взрослых, дозированный

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Если у Вас одно из перечисленных заболеваний, перед приемом препарата обязательно проконсультируйтесь с врачом."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Применение препарата при беременности и в период грудного вскармливания противопоказано."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Интраназально."}},{"type":"paragraph","data":{"text":"Для лиц и пациентов старше 18 лет: по 1 впрыскиванию в каждый носовой ход 3 раза в сутки. Между двумя впрыскиваниями должно пройти не менее 6 часов."}},{"type":"paragraph","data":{"text":"Препарат применяется не более 7 дней без консультации врача."}},{"type":"paragraph","data":{"text":"Перед первым применением спрея нажать на помповое дозирующее устройство несколько раз до выхода полной дозы. При дальнейшем использовании дополнительная активация дозирующего устройства не требуется. Если наблюдается неравномерное дозирование спрея или перерыв в использовании препарата составил более 9 дней, необходимо повторно нажать несколько раз на помповое дозирующее устройство для его активации до выхода полной дозы. Рекомендуется прекратить лечение сразу после купирования симптомов, даже если это произошло ранее, чем через 7 дней (максимальная продолжительность терапии), с целью минимизации риска нежелательных явлений. Длительное применение ксилометазолина может вызвать отек слизистой оболочки носа и повышение секреции, что обусловлено развитием повышенной чувствительности клеток к действующим веществам препарата, так называемый эффект «рикошета»."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПрименение в пожилом возрасте:\u003c/i\u003e опыт применения препарата у лиц старше 70 лет ограничен."}},{"type":"paragraph","data":{"text":"Одно вспрыскивание препарата Ксимелин Экстра содержит около 70 мкг ксилометазолина гидрохлорида и 84 мкг ипратропия бромида."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Классификация частоты возникновения нежелательных реакций: очень часто (≥ 1/10); часто (≥ 1/100, ˂ 1/10); нечасто (≥ 1/1000, ˂ 1/100); редко (≥ 1/10000, ˂ 1/1000); очень редко (˂ 1/10000), включая отдельные сообщения и реакции с неизвестной частотой (не может быть рассчитана на основании доступных данных)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны иммунной системы\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Частота неизвестна: реакции гиперчувствительности (анафилактическая реакция, ангионевротический отек, сыпь, зуд, ларингоспазм)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны нервной системы\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Часто: нарушения вкуса, головная боль."}},{"type":"paragraph","data":{"text":"Нечасто: нарушения обоняния, головокружение, тремор."}},{"type":"paragraph","data":{"text":"Очень редко: бессонница, судороги, галлюцинации."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны органа зрения\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Нечасто: раздражение глаз, сухость глаз."}},{"type":"paragraph","data":{"text":"Частота неизвестна: повышение внутриглазного давления, мидриаз, боль в глазах, фотопсия, ухудшение состояния при закрытоугольной глаукоме, нарушение четкости зрительного восприятия, расширение зрачка, гало эффект (наличие в поле зрения радужных кругов вокруг источника света)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны сердца\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Нечасто: учащенное сердцебиение, наджелудочковая тахикардия, артериальная гипертензия."}},{"type":"paragraph","data":{"text":"Очень редко: аритмичный пульс."}},{"type":"paragraph","data":{"text":"Частота неизвестна: мерцательная аритмия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны дыхательной системы, органов грудной клетки и средостения\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Очень часто: носовое кровотечение, раздражение и/или сухость слизистой оболочки носоглотки."}},{"type":"paragraph","data":{"text":"Часто: ощущение жжения, покалывания, назальная гиперсекреция, чихание, заложенность носа (при частом и/или длительном применении препарата), сухость в горле, першение в горле, риналгия, ринорея."}},{"type":"paragraph","data":{"text":"Нечасто: язва слизистой оболочки носа, чихание, боль в глотке, кашель, дисфония."}},{"type":"paragraph","data":{"text":"Частота неизвестна: дискомфорт в области околоносовых пазух, спазм гортани, отек глотки."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны желудочно-кишечного тракта\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Часто: сухость во рту."}},{"type":"paragraph","data":{"text":"Нечасто: диспепсия, тошнота."}},{"type":"paragraph","data":{"text":"Частота неизвестна: затрудненное глотание."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны кожи и подкожных тканей\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Частота неизвестна: зуд, кожная сыпь, крапивница."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны почек и мочевыводящих путей\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Частота неизвестна: затрудненное мочеиспускание."}},{"type":"paragraph","data":{"text":"\u003ci\u003eОбщие расстройства и нарушения в месте введения\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Нечасто: дискомфорт, утомляемость."}},{"type":"paragraph","data":{"text":"Частота неизвестна: дискомфорт в грудной клетке, жажда."}},{"type":"paragraph","data":{"text":"Если любые из указанных в инструкции побочных эффектов усугубляются или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"После интраназального применения препарата Ксимелин Экстра острая передозировка маловероятна, т.к. всасывание препарата крайне незначительно."}},{"type":"paragraph","data":{"text":"В случае передозировки ксилометазолина для клинической картины характерны: головокружение, тошнота, потоотделение, понижение температуры тела, головная боль, брадикардия, нарушение аккомодации, артериальная гипертензия, угнетение дыхания, кома, судороги. Артериальная гипертензия может смениться артериальной гипотензией. Симптоматическую терапию необходимо проводить под наблюдением врача."}},{"type":"paragraph","data":{"text":"При чрезмерном использовании ипратропия бромида передозировка маловероятна в связи с крайне незначительным всасыванием вещества в кровь, но могут развиться сухость во рту, затруднение аккомодации, тахикардия. Лечение симптоматическое."}},{"type":"paragraph","data":{"text":"Значительная передозировка может вызвать симптомы, связанные с холинолитическим действием препарата со стороны ЦНС, включая галлюцинации, для устранения которых назначают ингибиторы холинэстеразы."}},{"type":"paragraph","data":{"text":"Соответствующие поддерживающие меры должны приниматься при любых подозрениях на передозировку. При необходимости показано незамедлительное симптоматическое лечение под наблюдением врача. Эти меры должны включать наблюдение за пациентом в течение шести часов. В случае тяжелого отравления с остановкой сердца реанимационные действия должны продолжаться не менее 1 часа."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Препарат несовместим с одновременным приемом ингибиторов моноаминоксидазы (МАО), три- и тетрациклических антидепрессантов, а также в случае приема указанных препаратов в течение предшествующих 2 недель. Одновременное использование или применение в течение предшествующих 2-х недель три- и тетрациклических антидепрессантов и симпатомиметических препаратов может усилить симпатомиметический эффект ксилометазолина, и поэтому не рекомендовано."}},{"type":"paragraph","data":{"text":"Симпатомиметические препараты вызывают высвобождение катехоламинов, в том числе норадреналина, обладающего сосудосуживающим эффектом, вследствие чего повышается артериальное давление. При значительном повышении артериального давления лечение препаратом Ксимелин Экстра следует отменить и провести симптоматическое лечение."}},{"type":"paragraph","data":{"text":"При сопутствующем назначении других препаратов, обладающих антихолинергической активностью, возможно усиление антихолинергического эффекта ипратропия бромида."}},{"type":"paragraph","data":{"text":"Вышеуказанные взаимодействия изучались индивидуально для обоих действующих веществ, входящих в состав препарата Ксимелин Экстра. В комбинации для обоих действующих веществ вышеуказанные взаимодействия не изучались."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Перед применением необходимо очистить носовые ходы."}},{"type":"paragraph","data":{"text":"Не следует применять в течение длительного времени, например, при хроническом рините."}},{"type":"paragraph","data":{"text":"Пациентов необходимо предупредить о недопустимости распыления препарата Ксимелин Экстра в глаза или вокруг глаз. При попадании препарата в глаза необходимо промыть их холодной водой."}},{"type":"paragraph","data":{"text":"Если симптомы заболевания ухудшаются или состояние больного не улучшается в течение 3-х дней приема Ксимелина Экстра, необходимо проконсультироваться с врачом."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Применение препарата в терапевтических дозах не влияет на способность к управлению транспортными средствами и использованию механизмов."}},{"type":"paragraph","data":{"text":"Передозировка или попадание препарата в глаза может оказывать влияние на способность к управлению транспортными средствами и использованию механизмов."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Спрей назальный дозированный 84 мкг/доза + 70 мкг/доза."}},{"type":"paragraph","data":{"text":"По 10 мл препарата (не менее 60 доз) в пластиковом флаконе, снабженном помповым дозирующим устройством с наконечником и защитным колпачком из полиэтилена."}},{"type":"paragraph","data":{"text":"По 1 флакону вместе с инструкцией по применению помещают в картонную пачку."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить при температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года. Не использовать по истечении срока годности."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nТакеда ГмбХ, Германия"}},{"type":"paragraph","data":{"text":"Takeda GmbH, Germany"}},{"type":"paragraph","data":{"text":"Роберт-Бош-Штрассе 8, 78224 Зинген, Германия"}},{"type":"paragraph","data":{"text":"Robert-Bosch-Strasse 8, 78224 Singen, Germany\n\n"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"\n\nООО «Такеда Фармасьютикалс»,"}},{"type":"paragraph","data":{"text":"119048 Москва, ул. Усачева, д.2, стр.1."}},{"type":"paragraph","data":{"text":"тел. + 7 (495) 933 55 11, факс + 7 (495) 502 16 25"}},{"type":"paragraph","data":{"text":"Электронная почта: \u003ca href=\"mailto:russia@takeda.com\"\u003erussia@takeda.com\u003c/a\u003e"}}]}],"source":null},"description_toggle":false,"short_description":"Ксилометазолин относится к группе местных сосудосуживающих средств (деконгестантов) с альфа-адреномиметическим действием, вызывает сужение кровеносных сосудов слизистой носа, устраняя, таким образом, отек и гиперемию слизистой оболочки носоглотки. Облегчает носовое дыхание при ринитах. Ипратропия бромид обладает антихолинергическим эффектом. При интраназальном применении уменьшает секрецию желез слизистой оболочки полости носа. В терапевтических концентрациях не раздражает слизистую, не вызывает гиперемию. 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