Бензидамин является нестероидным противовоспалительным препаратом, относится к группе индазолов. Оказывает противовоспалительное и местное обезболивающее действие, обладает антибактериальным, противогрибковым и антисептическим действием. Механизм действия препарата связан со стабилизацией клеточных мембран и ингибированием синтеза простагландинов.
Бензидамин оказывает антибактериальное и противогрибковое действие за счет быстрого проникновения через мембраны клеток микроорганизмов с последующим повреждением клеточных структур, нарушением метаболических процессов и лизосом клеток микроорганизмов.
Бензидамин обладает противогрибковым действием в отношении Candida albicans. Вызывает структурные модификации клеточной стенки грибов и их метаболических цепей и, таким образом, препятствует их репродукции, что явилось основанием для применения бензидамина при воспалительных процессах в ротовой полости, включая инфекционную этиологию.
Фармакокинетика:
При местном применении препарат хорошо абсорбируется через слизистые оболочки и проникает в воспаленные ткани.
Экскреция препарата происходит в основном почками в виде метаболитов и через кишечник.
Показания к применению
Симптоматическая терапия болевого синдрома воспалительных заболеваний полости рта и ЛОР-органов:
- гингивит, глоссит, стоматит (в том числе после лучевой химиотерапии);
- фарингит, ларингит, тонзиллит;
- кандидоз слизистой оболочки полости рта (в составе комбинированной терапии);
- калькулезное воспаление слюнных желез;
- после оперативных вмешательств и травм (тонзилэктомия, переломы челюсти);
- после лечения или удаления зубов;
- пародонтоз.
При инфекционных и воспалительных заболеваниях, требующих системного лечения, необходимо применение препарата в составе комбинированной терапии.
Противопоказания
Повышенная чувствительность к какому-либо компоненту препарата; детский возраст до 3 лет.
Применение при беременности и в период грудного вскармливания
В связи с отсутствием достаточных данных применение препарата во время беременности и в период грудного вскармливания возможно только по назначению врача.
Способ применения и дозы
Местно.
Взрослым и пациентам пожилого возраста назначают по 4-8 доз каждые 1,5-3 часа.
Детям в возрасте 3-6 лет - по 1-4 дозы (максимально - 4 дозы) каждые 1,5-3 часа.
Детям в возрасте 6-12 лет - по 4 дозы каждые 1,5-3 часа.
Курс лечения:
- при воспалительных заболеваниях полости рта и ЛОР-органов (различной этиологии): от 4 до 15 дней;
- при одонто-стоматологической патологии: от 6 до 25 дней;
- после оперативных вмешательств и травм (тонзилэктомия, переломы челюсти): от 4 до 7 дней.
При применении препарата в течение длительных сроков (более 7 дней), необходима консультация врача.
Побочное действие
Со стороны дыхательной системы: очень редко (< 0,01 %) - ларингоспазм.
Местные реакции: сухость во рту, чувство онемения, жжения в ротовой полости.
Аллергические реакции: кожная сыпь.
Передозировка
О случаях передозировки не сообщалось.
Взаимодействие с другими лекарственными средствами
Не установлено клинически значимого взаимодействия препарата Бронфлекс с другими лекарственными средствами.
Особые указания
Следует избегать попадания спрея в глаза.
Влияние на способность управлять автомобилем и движущимися механизмами
Препарат не оказывает влияния на способность управлять транспортными средствами и механизмами.
Форма выпуска
Спрей для местного применения дозированный 0,27 мг/доза.
Условия хранения
При температуре не выше 25 °С.
Хранить в недоступном для детей месте в оригинальной упаковке.
Срок годности
3 года.
Не использовать после истечения срока годности.
Условия отпуска
Без рецепта
Производитель
Абди Ибрахим Иляч Санайи ве Тидж А.Ш., Sanayi Mahallesi Tunc Caddesi No: 3 Esenyurt, Istanbul, Turkey, Турция
Организация, принимающая претензии потребителей
АО "Санофи-авентис груп"
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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