Грибковые инфекции кожи и кожных складок (tinea corporis, tinea inquinalis); межпальцевые микозы (tinea manum, tinea pedum); грибковые инфекции ногтей (онихомикозы); кожный кандидоз; отрубевидный лишай; дерматомикозы (с сопутствующим зудом или без него). Эффективен при лечении микозов, поражающих области кожи с гиперкератозом, а также в зонах роста ...
Гиперчувствительность к нафтифину или пропиленгликолю. Препарат нельзя наносить на раневую поверхность. С осторожностью: детский возраст (опыт клинического применения ограничен).
В 1 мл раствора содержится нафтифина гидрохлорид 10 мг. Вспомогательные вещества: пропиленгликоль — 50 мг; этанол — 400 мг; вода очищенная — 475 мг
Фармакологические свойства
Нафтифин — противогрибковое средство для наружного применения, относящееся к классу аллиламинов. Механизм действия связан с ингибированием сквален-2,3-эпоксидазы, что приводит к снижению образования эргостерола, входящего в состав клеточной стенки гриба. Активен в отношении дерматофитов, таких как трихофитон, эпидермофитон и микроспорум, плесеней (Aspergillus spp.), дрожжевых грибов (Candida spp., Pityrosporum) и других грибов (например, Sporothrix schenckii). В отношении дерматофитов и аспергилл нафтифин действует фунгицидно. В отношении дрожжевых грибов препарат проявляет фунгицидную или фунгистатическую активность в зависимости от штамма микроорганизма. Обладает антибактериальной активностью в отношении грамположительных и грамотрицательных микроорганизмов, которые могут вызвать вторичные бактериальные инфекции. Обладает противовоспалительным действием, которое способствует быстрому исчезновению симптомов воспаления, особенно зуда
Показания к применению
Грибковые инфекции кожи и кожных складок (tinea corporis, tinea inquinalis); межпальцевые микозы (tinea manum, tinea pedum); грибковые инфекции ногтей (онихомикозы); кожный кандидоз; отрубевидный лишай; дерматомикозы (с сопутствующим зудом или без него). Эффективен при лечении микозов, поражающих области кожи с гиперкератозом, а также в зонах роста волос
Противопоказания
Гиперчувствительность к нафтифину или пропиленгликолю. Препарат нельзя наносить на раневую поверхность. С осторожностью: детский возраст (опыт клинического применения ограничен).
Применение при беременности и в период грудного вскармливания
Безопасность и эффективность применения не определены
Способ применения и дозы
НаружноПри поражении кожи Экзодерил наносят 1 раз в день на пораженную поверхность кожи и соседние с ней участки (приблизительно 1 см здорового участка кожи по краям зоны поражения) после их тщательной очистки и высушивания. Длительность терапии при дерматомикозах — 2–4 нед (при необходимости — до 8 нед), при кандидозах — 4 нед. При поражении ногтей Экзодерил наносят 2 раза в день на пораженный ноготь. Перед первым применением препарата максимально удаляют пораженную часть ногтя ножницами или пилкой для ногтей. Длительность терапии при онихомикозах — до 6 мес. Для предотвращения рецидива лечение следует продолжить в течение минимум 2 нед после исчезновения клинических симптомов
Побочное действие
В отдельных случаях могут наблюдаться местные реакции: сухость кожи, гиперемия и жжение. Побочное эффекты носят обратимый характер и не требуют отмены лечения
Передозировка
О случаях передозировки не сообщалось
Взаимодействие с другими лекарственными средствами
Не отмечено лекарственного взаимодействия препарата Экзодерил с другими препаратами.
Особые указания
Препарат Экзодерил не предназначен для применения в офтальмологии. Не следует допускать попадания препарата в глаза.
Влияние на способность управлять автомобилем и движущимися механизмами
Экзодерил® не оказывает отрицательного влияния на способность управлять транспортными средствами и выполнять другие виды деятельности, требующие концентрации внимания и быстроты психомоторных реакций.
Форма выпуска
Раствор.
Условия отпуска
Без рецепта.
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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