Флорацид Таблетки, 10 шт, 500 мг, для приема внутрь

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Инфекции кожи и мягких тканей: по 250 мг 1 раз в день или по 500 мг 1–2 раза в день. Продолжительность лечения — 7–14 дней. Интраабдоминальная инфекция: по 500 мг 1 раз в день. Продолжительность лечения — 7–14 дней (в комбинации с антибактериальными препаратами, действующими на анаэробную флору). Комплексное лечение лекарственноустойчивых форм туберкулеза: по 500 мг 1–2 раза в день. Продолжительность лечения — до 3 мес."}}]},{"id":8,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Аллергические реакции: иногда — зуд и покраснение кожи, редко — крапивница, бронхоспазм, удушье, очень редко — отеки кожи и слизистых оболочек (например в области лица и гортани), анафилактический шок, аллергический пневмонит, васкулит, в отдельных случаях — синдром Стивенса-Джонсона, токсический эпидермальный некролиз (синдром Лайелла) и экссудативная многоформная эритема. Со стороны пищеварительной системы: часто — тошнота, диарея, повышение активности АЛТ, ACT, иногда — потеря аппетита, рвота, боли в животе, нарушение пищеварения, редко — повышение уровня билирубина в сыворотке крови, диарея с кровью (в очень редких случаях может являться признаком воспаления кишечника и псевдомембранозного колита), дисбактериоз, очень редко — гепатит. Со стороны обмена веществ: очень редко — гипогликемия (проявляющаяся резким повышением аппетита, нервозностью, испариной, дрожью). Опыт применения других хинолонов свидетельствует о том, что они способны вызывать обострение порфирии, в отдельных случаях подобный эффект не исключается и при применении левофлоксацина. Со стороны ЦНС и периферической нервной системы: иногда — головная боль, головокружение и/или оцепенение, сонливость, нарушение сна, редко — депрессия, беспокойство, психотические реакции (например галлюцинации), парестезии в кистях рук, дрожь, возбужденное состояние, судороги и спутанность сознания, очень редко — нарушения зрения и слуха, нарушения вкусовой чувствительности и обоняния, понижение тактильной чувствительности. Со стороны ССС: редко — тахикардия, снижение АД, очень редко — сосудистый коллапс, в отдельных случаях — удлинение интервала QT. Со стороны опорно-двигательного аппарата: редко — поражения сухожилий (включая тендинит), суставные и мышечные боли, очень редко — разрыв сухожилий (например ахиллова сухожилия может наблюдаться в течение 48 ч после начала лечения и носить двусторонний характер), артралгия, миалгия, мышечная слабость, имеющая особое значение для больных с бульбарным синдромом, в отдельных случаях — поражения мышц (рабдомиолиз). Со стороны мочевыделительной системы: редко — повышение уровня креатинина в сыворотке крови, очень редко — нарушение функции почек вплоть до острой почечной недостаточности, интерстициальный нефрит. Со стороны органов кроветворения: иногда — эозинофилия, лейкопения, редко — нейтропения, тромбоцитопения, геморрагии, очень редко — агранулоцитоз, в отдельных случаях — гемолитическая анемия, панцитопения. Прочие: иногда — астения, очень редко — развитие суперинфекций, лихорадка, фотосенсибилизация."}}]},{"id":9,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Симптомы: спутанность сознания, головокружение, нарушение сознания, судороги по типу эпилептических припадков, могут отмечаться желудочно-кишечные расстройства (например, тошнота) и эрозивные поражения слизистых оболочек, отмечается удлинение интервала QT. Лечение: проводят симптоматическую терапию. Левофлоксацин не выводится при помощи гемодиализа, перитонеального диализа и постоянного перитонеального диализа. Специфического антидота не существует."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"\n\nХинолоны могут усиливать способность препаратов (в т.ч. НПВС, теофиллина) понижать порог судорожной готовности. Действие левофлоксацина значительно ослабляется при одновременном применении с сукральфатом, магний- или алюминийсодержащими антацидами, а также солями железа. Поэтому левофлоксацин следует применять не менее чем за 2 ч до или через 2 ч после приема этих средств. Не выявлено взаимодействия левофлоксацина с карбонатом кальция. При одновременном применении левофлоксацина и антагонистов витамина К необходим контроль за свертывающей системой крови. Выведение (почечный клиренс) левофлоксацина незначительно замедляется под действием циметидина и пробенецида. Следует отметить, что это взаимодействие практически не имеет никакого клинического значения. Левофлоксацин незначительно увеличивает T1/2 циклоспорина. При одновременном применении левофлоксацина с ГКС повышается риск разрыва сухожилий.\n\n"}}]},{"id":10,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"При тяжелом воспалении легких, вызванном пневмококками, применение левофлоксацина может бать не достаточно эффективным. Госпитальные инфекции, вызванные Pseudomonas aeruginosa, могут потребовать применения комбинированной терапии. Во время лечения препаратом возможно развитие судорог у больных с предшествующим поражением головного мозга, обусловленным, например, инсультом или тяжелой травмой. Судорожная готовность может повышаться и при одновременном применении фенбуфена, сходных с ним НПВС или теофиллина. Во избежание развития фотосенсибилизации в период лечения Флорацидом больным следует избегать пребывания на солнце или УФ-облучения. При подозрении на псевдомембранозный колит следует немедленно отменить Флорацид и начать соответствующее лечение. В таких случаях нельзя применять лекарственные средства, угнетающие моторику кишечника. Редко наблюдаемый при применении левофлоксацина тендинит (прежде всего воспаление ахиллова сухожилия) может приводить к разрыву сухожилий. Больные пожилого возраста более склонны к тендиниту. Лечение кортикостероидами по всей вероятности повышает риск разрыва сухожилий. При подозрении на тендинит следует немедленно прекратить лечение препаратом и начать соответствующее лечение пораженного сухожилия. При применении хинолонов у пациентов с недостаточностью глюкозо-6-фосфатдегидрогеназы возможен гемолиз эритроцитов. Учитывая это, лечение Флорацидом данной категории пациентов следует проводить с особой осторожностью. При применении препарата у пациентов с сахарным диабетом следует иметь в виду, что Флорацид может вызывать гипогликемию. В период лечения следует избегать употребления алкоголя. Влияние на способность к вождению автотранспорта и управлению механизмами Флорацид может вызывать головокружение или скованность, сонливость, нарушения зрения, а также снижать способность к концентрации внимания и скорость психомоторных реакций. Это следует учитывать при необходимости применения препарата у лиц, деятельность которых связана с управлением автомобилем, обслуживанием машин и механизмов, с выполнением работ в неустойчивом положении."}}]},{"id":17,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки."}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В защищенном от света месте, при температуре не выше 25 °C. Хранить в недоступном для детей месте."}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года."}}]},{"id":20,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"По рецепту."}}]},{"id":21,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.eapteka.ru/goods/manufacturer/valenta_farma/\"\u003eВалента Фарм, Россия\u003c/a\u003e."}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"Флорацид - антибактериальный препарат группы фторхинолонов. Левофлоксацин - левовращающий изомер офлоксацина. Левофлоксацин блокирует ДНК-гиразу, нарушает суперспирализацию и сшивку разрывов ДНК, вызывает глубокие морфологические изменения в цитоплазме, клеточной стенке и мембране бактерий. Флорацид активен в отношении аэробных грамположительных бактерий: Corynebacterium diphtheriae, Enterococcus faecalis, Enterococcus spp., Listeria monocytogenes, Staphylococcus spp. (коагулаза-отрицательные метициллин-чувствительные, метициллин-умеренно чувствительные штаммы), в т.ч. Staphylococcus aureus (метициллин-чувствительные штаммы), Staphylococcus epidermidis (метициллин-чувствительные штаммы), Streptococcus spp. группы С и G, Streptococcus agalactiae, Streptococcus pneumoniae (пенициллин-чувствительные, умеренно чувствительные, резистентные штаммы), Streptococcus pyogenes, Streptococcus viridans (пенициллин-чувствительные, резистентные штаммы), аэробных грамотрицательных бактерий: Acinetobacter spp. (в т.ч. Acinetobacter baumannii), Actinobacillus actinomycetemcomitans, Citrobacter freundii, Eikenella corrodens, Enterobacter spp. (в т.ч. Enterobacter aerogenes, Enterobacter agglomerans, Enterobacter cloacae), Escherichia coli, Gardnerella vaginalis, Haemophilus ducreyi, Haemophilus influenzae (ампициллин-чувствительные, резистентные штаммы), Наеmophilus parainfluenzae, Helicobacter pylori, Klebsiella spp. (в т.ч. Klebsiella oxytoca, Klebsiella pneumoniae), Moraxella catarrhalis, Morganella morganii, Neisseria gonorrhoeae, Neisseria meningitidis, Pasteurella spp. (в т.ч. Pasteurella canis, Pasteurella dagmatis, Pasteurella multocida), Proteus mirabilis, Proteus vulgaris, Providencia spp. (в т.ч. Providencia rettgeri, Providencia stuartii), Pseudomonas spp. (в т.ч. Pseudomonas aeruginosa), Salmonella spp., Serratia spp. (в т.ч. Serratia marcescens), анаэробных бактерий: Bacteroides fragilis, Bifidobacterium spp., Clostridium perfringens, Fusobacterium spp., Peptostreptococcus spp., Propionibacterium spp., Veilonella spp. Активен также в отношении: Bartonella spp., Chlamydia pneumoniae, Chlamydia psittaci, Chlamydia trahomatis, Legionella pneumophila, Legionella spp., Mycobacterium spp. (в т.ч. Mycobacterium leprae, Mycobacterium tuberculosis), Mycoplasma hominis, Mycoplasma pneumoniae, Rickettsia spp., Ureaplasma.","substance":[{"id":263,"title":"Левофлоксацин","title_latin":"Levofloxacinum","slug":"levofloksatsin_263"}],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":null,"image_alt":"Флорацид - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/90461/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/90461/share_default/"}},"diseases":[{"id":"59","title":"Хламидийные инфекции нижних отделов мочеполового тракта","slug":"59-hlamidiynye_infektsii_nizhnih_otdelov_mochepolovogo_trakta"},{"id":"696","title":"Гнойный и неуточненный средний отит","slug":"696-gnoynyy_i_neutochnennyy_sredniy_otit"},{"id":"790","title":"Острый синусит","slug":"790-ostryy_sinusit"},{"id":"802","title":"Бактериальная пневмония, не классифицированная в других 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