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Применение в I и II триместрах возможно только после консультации с врачом, если ожидаемая польза для матери превышает потенциальный риск для плода."}},{"type":"paragraph","data":{"text":"Применение в период грудного вскармливания противопоказано."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Наружно. Взрослым и детям старше 12 лет препарат наносят тонким слоем над очагом воспаления 3-4 раза в день и слегка втирают. Необходимое количество препарата зависит от размера болезненной зоны. Разовая доза препарата: 2-4 г (что по объему сопоставимо с размером крупной вишни)."}},{"type":"paragraph","data":{"text":"После нанесения препарата необходимо вымыть руки."}},{"type":"paragraph","data":{"text":"Длительность лечения зависит от показаний и лечебного эффекта. После 2-х недель использования препарата следует проконсультироваться с врачом."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Классификация частоты возникновения побочных эффектов: очень часто (≥1/10), часто (≥1/100 и <1/10), нечасто (≥1/1000 и <1/100), редко (≥1/10000 и <1/1000), очень редко (< 1/10000)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eИнфекционные и паразитарные заболевания:\u003c/i\u003e очень редко — пустулезная сыпь."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны иммунной системы:\u003c/i\u003e очень редко — реакции гиперчувствительности (в т. ч. крапивница), ангионевротический отек."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны дыхательной системы, органов грудной клетки и средостения:\u003c/i\u003e очень редко — астма."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны кожи и подкожных тканей:\u003c/i\u003e часто — дерматит (включая контактный дерматит), сыпь, эритема, экзема, зуд; редко — буллезный дерматит; очень редко — реакции фотосенсибилизации."}},{"type":"paragraph","data":{"text":"Если у Вас развился какой-то побочный эффект, указанный в инструкции, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы:\u003c/i\u003e ввиду низкой системной абсорбции при аппликации геля, передозировка маловероятна. При случайном приеме внутрь возможно развитие системных побочных реакций."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение:\u003c/i\u003e промывание желудка, индукция рвоты, активированный уголь, симптоматическая терапия. Форсированный диурез и гемодиализ не эффективны ввиду высокой степени связывания диклофенака с белками плазмы крови (около 99%)."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Диклофенак может усиливать действие препаратов, вызывающих фотосенсибилизацию."}},{"type":"paragraph","data":{"text":"Клинически значимые взаимодействия с другими лекарственными препаратами не описаны."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Гель наносят только на неповрежденные участки кожи. После наложения не следует накладывать окклюзионную повязку."}},{"type":"paragraph","data":{"text":"При нанесении на большие поверхности кожи в течение длительного времени повышается риск развития системных побочных эффектов."}},{"type":"paragraph","data":{"text":"Следует избегать попадания препарата в глаза, на слизистые оболочки или открытые раны."}},{"type":"paragraph","data":{"text":"Применять только как наружное средство."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Не влияет."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Гель для наружного применения 1%."}},{"type":"paragraph","data":{"text":"По 40 г в тубы алюминиевые, укупоренные навинчивающейся крышечкой из пластмассы. Отверстие тубы защищено алюминиевой мембраной. Крышечка представляет собой монолитную конструкцию, включающую в себя приспособление для прокалывания мембраны."}},{"type":"paragraph","data":{"text":"Каждую тубу вместе с инструкцией по медицинскому применению лекарственного препарата в пачку из картона."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"При температуре от 15 до 25°С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте!"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года. Не использовать по истечении срока годности, указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают без рецепта."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nХемофарм А.Д. Вршац, отделение Производственная площадка Шабац, Сербия"}},{"type":"paragraph","data":{"text":"15000, г. Шабац, ул. Хайдук Велькова бб\n\n"}}]}],"source":null},"description_toggle":false,"short_description":"ФармакодинамикаНестероидный противовоспалительный препарат, производное фенилуксусной кислоты, оказывает противовоспалительное и анальгезирующее действие. Неизбирательно угнетая циклооксигеназу 1 (ЦОГ1) и циклооксигеназу 2 (ЦОГ2), воздействует на метаболизм арахидоновой кислоты, уменьшает количество простагландинов, являющихся основным звеном в развитии воспаления. При воспалительных процессах способствует устранению боли и уменьшению отечности в области нанесения препарата.ФармакокинетикаПри местном применении частично всасывается через кожу, биодоступность — 6%. Связь с белками плазмы — 99,7%. Выводится почками. 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