Эмла Крем, туба, 30 г, 5 %, для местного и наружного применения

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Действие препарата обеспечивается входящими в его состав компонентами - лидокаином и прилокаином, которые являются местными анестетиками амидного типа. Местные анестетики, проникая в слои эпидермиса и дермы, вызывают анестезию кожи. ; Степень анестезии зависит от дозы препарата и длительности аппликации. ; После нанесения крема на интактную кожу на 1-2 ч продолжительность анестезии после снятия окклюзионной повязки составляет 2 ч. При пункционной биопсии применение крема Эмла обеспечивает адекватную анестезию интактной кожи у 90% пациентов через 60 мин после нанесения. ; Анестезия слизистой оболочки половых органов достигается быстрее, чем интактной кожи, из-за более быстрой абсорбции препарата. У женщин через 5-10 мин после нанесения крема Эмла на слизистую оболочку половых органов достигается анестезия, достаточная для купирования боли, вызванной использованием аргонового лазера; продолжительность анестезии составляет 15-20 мин (с учетом индивидуальных особенностей от 5 до 45 мин). ; При обработке трофических язв нижних конечностей продолжительность анестезии после нанесения крема составляет до 4 ч. Не отмечено негативного действия препарата на процесс заживления язв или в отношении бактериальной флоры."}}]},{"id":3,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Поверхностная анестезия: - кожи при пункциях и катетеризации сосудов и поверхностных хирургических вмешательствах; - трофических язв нижних конечностей при хирургической обработке (механической очистке); - слизистой оболочки половых органов перед проведением болезненных манипуляций и для обезболивания перед инъекциями местных анестетиков."}}]},{"id":4,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"повышенная чувствительность к местным анестетикам амидного типа или любому другому компоненту препарата."}},{"type":"paragraph","data":{"text":"недоношенные новорожденные, родившиеся при сроке беременности менее 37 недель."}},{"type":"paragraph","data":{"text":"новорожденные с массой тела менее 3 кг."}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Возможно применение препарата Эмла при беременности и в период лактации по показаниям и в рекомендуемых дозах. ; Лидокаин и прилокаин выделяются с грудным молоком в количествах, не представляющих риска для младенца."}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Наружно, на кожу или слизистую оболочку. ; Крем наносят под окклюзионную повязку (имеется в упаковке) не менее чем за 1 ч до начала процедуры, записывают на повязке время нанесения препарата, после снятия повязки вытирают остатки крема этанолом. ; Для анестезии кожи: взрослым (для проведения \"малых\" процедур) наносят 1.5 г/10 кв.см в течение 1-5 ч, на большие поверхности - 1.5-2 г/10 кв.см в течение 2-5 ч; детям от 3 до 11 мес. - до 1 г/20 кв.см. Детям старше 1 года - 1 г/10 кв.см. ; Анестезия половых органов - 5-10 г крема на 5-10 мин (без плотной повязки). ;"}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Местные реакции: часто (\u003e1%) - бледность, гиперемия и отечность в месте нанесения препарата (за счет действия на поверхностные сосуды); иногда (\u003c1%-\u003e0.1%) - легкое жжение и зуд сразу после нанесения препарата; редко (\u003c0.1%) - геморрагическая сыпь или точечные кровоизлияния, особенно после длительной аппликации у детей с распространенным нейродермитом или контагиозным моллюском. ; Системные реакции: редко (\u003c0.1%) - аллергические реакции (в тяжелых случаях - анафилактический шок), метгемоглобинемия у детей."}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Симптомы: возбуждение ЦНС, в тяжелых случаях - угнетение ЦНС и сердечной деятельности. В отдельных случаях у детей отмечалось развитие клинически значимой метгемоглобинемии. ; Нанесение 125 мг прилокаина продолжительностью 5 ч вызвало развитие умеренной метгемоглобинемии у трехмесячного ребенка. Нанесение лидокаина в дозе 8.6-17.2 мг/кг вызывало выраженную интоксикацию у новорожденных. ; Лечение: следует удалить невсосавшуюся часть препарата с поверхности кожи. При возникновении симптомов со стороны ЦНС (судороги, угнетение ЦНС) показано проведение симптоматической терапии, в т.ч. назначение противосудорожной терапии и при необходимости - ИВЛ. При развитии метгемоглобинемии в качестве антидота следует использовать метиленовый синий. 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