Фармакологическое действие — отхаркивающее, муколитическое. Инструкция
Показания к применению
Препарат показан для лечения взрослых, подростков и детей с массой тела более 15 кг в следующих случаях: -острые воспалительные заболевания дыхательных путей: ларингофарингит, острый бронхит; -ринит, синусит; -обострения хронических заболеваний дыхательных путей: хронический бронхит, ХОБЛ, гиперсекреторная астма, бронхоэктатическая болезнь, хронический ...
Гиперчувствительность к входящим в состав препарата ингредиентам, содержащим свободные SH-радикалы; -нарушение функции печени; -почечная недостаточность (Cl креатинина <25 мл/мин); -гомоцистинурия (препарат является источником гомоцистеина, поэтому возможны нарушения метаболизма аминокислот у пациентов, находящихся на диете со сниженным содержанием ...
Фармакологическое действие — отхаркивающее, муколитическое.
Показания к применению
Препарат показан для лечения взрослых, подростков и детей с массой тела более 15 кг в следующих случаях: -острые воспалительные заболевания дыхательных путей: ларингофарингит, острый бронхит; -ринит, синусит; -обострения хронических заболеваний дыхательных путей: хронический бронхит, ХОБЛ, гиперсекреторная астма, бронхоэктатическая болезнь, хронический бронхит курильщиков (включая сезонные обострения); -комплексная терапия (с антибиотиками): обострение бронхита бактериальной этиологии; -профилактика пневмонии и частичного ателектаза после хирургических вмешательств.
Противопоказания
Гиперчувствительность к входящим в состав препарата ингредиентам, содержащим свободные SH-радикалы; -нарушение функции печени; -почечная недостаточность (Cl креатинина <25 мл/мин); -гомоцистинурия (препарат является источником гомоцистеина, поэтому возможны нарушения метаболизма аминокислот у пациентов, находящихся на диете со сниженным содержанием свободного метионина); -фенилкетонурия (для гранул для приготовления суспензии и раствора, т.к. в их состав входит аспартам); -беременность (I триместр); -детский возраст (до 2 лет). С осторожностью: -нерациональное применение с противокашлевой терапией (возможно скопление жидкого секрета в бронхах и увеличение риска развития суперинфекции или бронхоспазма); -почечная недостаточность (возможна кумуляция метаболитов); -выраженное нарушение функции печени (возможно увеличение T1/2).
Применение при беременности и в период грудного вскармливания
Преклинические исследования не выявили эмбриотоксического действия. Однако опыт применения препарата в период беременности и грудного вскармливания ограничен. Поэтому применение препарата в период беременности (особенно I триместр) и лактации следует проводить только по строгим показаниям.
Способ применения и дозы
Внутрь. Взрослым. Капсулы — по 1 капс. (300 мг) 2–3 раза в день. Гранулы для приготовления суспензии для приема внутрь — по 8,5 мл (300 мг) 2 раза в день. Дозировка на вес тела: 10 мг/кг массы тела 2 раза в день. Гранулы для приготовления раствора для приема внутрь — по 1 саше (225 мг) 2–3 раза в день. Детям. Рекомендуемая форма — гранулы для приготовления суспензии для приема внутрь. Режим дозирования определяется на основании массы тела и возраста следующим образом: 15–20 кг (от 3 до 6 лет) — по 2,5 мл 2 раза в день; 21–30 кг (от 7 до 12 лет) — по 5 мл 2 раза в день; свыше 30 кг (старше 12 лет) — по 5 мл 3 раза в день. Метод приготовления Гранулы для приготовления суспензии: заливают водой содержимое флакона (сухой гранулят) до специальной метки. Тщательно встряхивают, пока не образуется однородная суспензия. Проверяют уровень содержимого во флаконе и (если необходимо) добавляют воды и снова встряхивают флакон. Готовая суспензия может использоваться максимум в течение 10 дней, если будет храниться в холодильнике при температуре 2–8 °C. Перед каждым употреблением встряхивают. Гранулы для приготовления раствора для приема внутрь: содержимое саше растворяют в стакане воды или чая и принимают внутрь.
Побочное действие
Со стороны органов ЖКТ: редко — изжога, тошнота, диарея. Очень редко в начале лечения — возможна утрата или изменение вкусовой чувствительности. Аллергические реакции: редко — покраснение кожи, крапивница.
Передозировка
О случаях передозировки не сообщалось. Лечение: в случае передозировки или при случайном употреблении детьми рекомендуется применение симптоматической терапии.
Особые указания
Препарат не оказывает какого-либо влияния на способность управлять автомобилем или другими механизмами.
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