Генферон лайт Спрей, флакон, 100 д, 50000 МЕ, назальный

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Разрешено к применению у беременных женщин."}},{"type":"paragraph","data":{"text":"Генферон Лайт спрей— максимум в 1 дозе. Комфортно, современно, удобно."}},{"type":"paragraph","data":{"text":"Генферон Лайт — единственная в России комбинация интерферона и таурина** для лечения и профилактики ОРВИ и гриппа. Прошел испытания в 9 крупных клинических исследованиях на 1579 пациентах."}},{"type":"paragraph","data":{"text":"Преимущества препарата Генферон Лайт спрей."}},{"type":"paragraph","data":{"text":"1. Активно борется с вирусами и батериями в месте их вторжения — полости носа."}},{"type":"paragraph","data":{"text":"2. Обладает универсальным противовирусным действием."}},{"type":"paragraph","data":{"text":"3. Активирует защитный местный иммунитет."}},{"type":"paragraph","data":{"text":"4. Содержит глицерол*****, известный своими увлажняющими свойствами***,****."}},{"type":"paragraph","data":{"text":"5. Содержит масло мяты*****"}},{"type":"paragraph","data":{"text":"Преимущества формы выпуска."}},{"type":"paragraph","data":{"text":"1. Дозированная насадка-распылитель Генферон Лайт в форме спрея обеспечивает комфортное использование и точность дозы: 1 нажатие — 1 доза 50 тыс МЕ препарата"}},{"type":"paragraph","data":{"text":"2. Генферон Лайт в форме спрея обеспечивает мелкодисперсное («‎туманообразное») распыление препарата для создания равномерного распределения по всей поверхности носоглотки, помогая блокировать вирусное вторжение."}},{"type":"paragraph","data":{"text":"3. Специальная конструкция флакона с насосом обеспечивает полное использование противовирусного средства без остатка."}},{"type":"paragraph","data":{"text":"4. Экономичность спрея Генферон Лайт: в одном флаконе противовирусного спрея содержится 100 доз. Можно использовать в течение нескольких эпизодов простудных заболеваний или для профилактики в течение всего простудного сезона."}},{"type":"paragraph","data":{"text":"5. Использовать вскрытый флакон Генферон Лайт можно до конца срока годности препарата."}},{"type":"paragraph","data":{"text":"6. Можно сочетать с другими лекарственными средствами (симптоматическими, этиотропными)."}},{"type":"paragraph","data":{"text":"7. Для формы спрея не характерны побочные эффекты со стороны желудка, свойственные перроральным лекарственным средствам."}},{"type":"paragraph","data":{"text":"*Максимальная дозировка ИФН альфа 2b - 50 000 MЕ в 1 дозе, среди назальных интерферонов, согласно ГРЛС март 2020."}},{"type":"paragraph","data":{"text":"**По данным ГРЛС март 2020."}},{"type":"paragraph","data":{"text":"***Раймонд КР и др. Настольная книга фармацевтических вспомогательных веществ. Шестое издание. 2009 (Raymond C Rowe, Paul J Sheskey, Marian E Quinn. Handbook of Pharmaceutical Excipients. Sixth edition. 2009)."}},{"type":"paragraph","data":{"text":"****Мари Луден и др. Дерматология: серия клинических и фундаментальных наук. Сухость кожи и увлажняющие средства. Второе издание. 2006 (Marie Loden, Howard I. Maibach. Dermatology: Clinical&Basic science series. Dry skin and moisturizers. Chemistry and Function. 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Противовирусный эффект опосредован активацией ряда внутриклеточных ферментов, ингибирующих репликацию вирусов. Иммуномодулирующее действие проявляется, в первую очередь, усилением клеточно-опосредованных реакций иммунной системы, что повышает эффективность иммунного ответа в отношении вирусов, внутриклеточных паразитов и клеток, претерпевших опухолевую трансформацию. Это достигается за счет активации CD8+ Т-киллеров, NK-клеток (естественных киллеров), усилении дифференцировки В-лимфоцитов и продукции ими антител, активации моноцитарно-макрофагальной системы и фагоцитоза, а также повышении экспрессии молекул главного комплекса гистосовместимости I типа, что повышает вероятность распознавания инфицированных клеток клетками иммунной системы. Активизация под воздействием интерферона лейкоцитов, содержащихся во всех слоях слизистой оболочки, обеспечивает их активное участие в ликвидации патологических очагов; кроме того, за счет влияния интерферона достигается восстановление продукции секреторного иммуноглобулина А. Антибактериальный эффект опосредован реакциями иммунной системы, усиливаемыми под влиянием интерферона."}},{"type":"paragraph","data":{"text":"Таурин способствует нормализации метаболических процессов и регенерации тканей, обладает мембраностабилизирующим и иммуномодулирующим действием. Являясь сильным антиоксидантом, таурин непосредственно взаимодействует с активными формами кислорода, избыточное накопление которых способствует развитию патологических процессов. Таурин способствует сохранению биологической активности интерферона, усиливая терапевтический эффект применения препарата."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Профилактика и лечение гриппа и ОРВИ у взрослых и детей старше 14 лет"}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"\n\nГиперчувствительность к интерферону альфа-2b или другим компонентам препарата."}},{"type":"paragraph","data":{"text":"Детский возраст до 14 лет.\n\n"}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"Следует с осторожностью назначать пациентам, страдающим носовыми кровотечениями."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Допускается применение в течение всего периода беременности, препарат не имеет ограничений к применению в период грудного вскармливания."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"\n\nПрепарат применяют интраназально путем аэрозольного введения 1 дозы (1 доза = 1 короткое нажатие на дозатор)."}},{"type":"paragraph","data":{"text":"При первых признаках заболевания Генферон лайт вводят интраназально в течение 5 дней по одной дозе (одно нажатие на дозатор) в каждый носовой ход 3 раза в день (одна доза приблизительно составляет 50 000 МЕ интерферона альфа, суточная не должна превышать 500 000 МЕ)."}},{"type":"paragraph","data":{"text":"При контакте с больным ОРВИ и/или при переохлаждении препарат вводят по указанной схеме 2 раза в день в течение 5-7 дней. При необходимости профилактические курсы повторяют."}},{"type":"paragraph","data":{"text":"Инструкция по применению спрея:"}},{"type":"paragraph","data":{"text":"1. Удалите защитный колпачок."}},{"type":"paragraph","data":{"text":"2. Перед употреблением в первый раз нажмите на дозатор несколько раз до появления тонкой струи."}},{"type":"paragraph","data":{"text":"3. При употреблении держите флакон в вертикальном положении."}},{"type":"paragraph","data":{"text":"4. Произведите впрыскивание препарата однократным нажатием на дозатор в каждый носовой ход поочередно."}},{"type":"paragraph","data":{"text":"5. После употребления закройте дозатор защитным колпачком."}},{"type":"paragraph","data":{"text":"Во избежание распространения инфекции рекомендовано индивидуальное использование.\n\n"}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\n\nВозможны аллергические реакции, кровянистые выделения из носа."}},{"type":"paragraph","data":{"text":"Как правило, указанные реакции носят легкий характер и не требуют дополнительной лекарственной терапии.\n\n"}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"О случаях передозировки препарата Генферон лайт не сообщалось."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Не рекомендуется одновременное применение интраназальных сосудосуживающих препаратов, так как это способствует дополнительному высушиванию слизистой оболочки носа."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"не влияет"}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Спрей назальный дозированный 50 000 МЕ/доза + 1 мг/доза."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"\n\nПри температуре от 2 до 8 °С в защищенном от света месте."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте.\n\n"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года. Не применять по истечении срока годности, указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"ЗАО «БИОКАД»"}}]}],"source":null},"description_toggle":false,"short_description":"В состав препарата Генферон Лайт входит рекомбинантный человеческий интерферон альфа-2b, вырабатываемый штаммом бактерии Escherichia coli, в которую методами генной инженерии введен ген интерферона альфа-2b человека. Интерферон альфа-2b оказывает противовирусное, иммуномодулирующее, антипролиферативное и антибактериальное действие. Противовирусный эффект опосредован активацией ряда внутриклеточных ферментов, ингибирующих репликацию вирусов. Иммуномодулирующее действие проявляется, в первую очередь, усилением клеточно-опосредованных реакций иммунной системы, что повышает эффективность иммунного ответа в отношении вирусов, внутриклеточных паразитов и клеток, претерпевших опухолевую трансформацию. Это достигается за счет активации CD8+ Т-киллеров, NK-клеток (естественных киллеров), усилении дифференцировки В-лимфоцитов и продукции ими антител, активации моноцитарно-макрофагальной системы и фагоцитоза, а также повышении экспрессии молекул главного комплекса гистосовместимости I типа, что повышает вероятность распознавания инфицированных клеток клетками иммунной системы. Активизация под воздействием интерферона лейкоцитов, содержащихся во всех слоях слизистой оболочки, обеспечивает их активное участие в ликвидации патологических очагов; кроме того, за счет влияния интерферона достигается восстановление продукции секреторного иммуноглобулина А. Антибактериальный эффект опосредован реакциями иммунной системы, усиливаемыми под влиянием интерферона. Таурин способствует нормализации метаболических процессов и регенерации тканей, обладает мембраностабилизирующим и иммуномодулирующим действием. Являясь сильным антиоксидантом, таурин непосредственно взаимодействует с активными формами кислорода, избыточное накопление которых способствует развитию патологических процессов. 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